General Cell Based Assays
Eurofins Discoverx PathHunter Human MIP-3β (CCRL1) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MIP-3β (CCRL1) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCRL1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress TIM3/TIM3 Dimerization Assay, 10-Plate Kit. (93-1082E3CP5L)
The PathHunter TIM3/TIM3 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand induced dimerization of TIM3/TIM3 receptors. This product uses EFC technology. The cell line included overexpresses TIM3 target protein fused to PK alongside TIM3 target protein fused to EA. Upon ligand-induced dimerization of TIM3/TIM3, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress SSTR2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0181E2CP0L)
The PathHunter SSTR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR2 and EA-tagged β-Arrestin-2. Activation of SSTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Free Fatty Acid Uptake Assay Kit (Fluorometric)
Free Fatty Acid Uptake Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tissue type Plasminogen Activator Activity Assay Kit (Colorimetric, Human)
Tissue type Plasminogen Activator Activity Assay Kit (Colorimetric, Human)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Human BDKRB2 β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Human BDKRB2 β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure BDKRB2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress IGF1R Functional Assay, 10-Plate Kit. (93-0505E1CP17L)
The PathHunter eXpress IGF1R Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated IGF1R dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged IGF1R and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress DRD2S (Short Isoform) CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0351E2CP0L)
The PathHunter DRD2S eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD2S GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD2S and EA-tagged β-Arrestin-2. Activation of DRD2S stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GHSR1a U2OS β-Arrestin-1 GPCR Assay, 2-Plate Kit. (93-0242E3CP5M)
The PathHunter GHSR1a (ARR1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. ghrelin) based activation of GHSR1a GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1a and EA-tagged β-Arrestin-1. Activation of GHSR1a stimulates the recruitment of β-Arrestin-1 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Phagocytosis Assay Kit (Green Zymosan)
Phagocytosis Assay Kit (Green Zymosan)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress CCR7 HEK 293 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0195E1CP0L)
The PathHunter CCR7 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL19/MIP-3β) based activation of CCR7 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR7 and EA-tagged β-Arrestin-2. Activation of CCR7 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR18 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0560E2ACP1L)
The PathHunter GPR18 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR18 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR18 and EA-tagged β-Arrestin-2. Activation of GPR18 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress FPRL1 Activated GPCR Internalization Assay, 10pl Kit. (93-0666E3CP0L)
The PathHunter FPRL1 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of FPRL1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged FPRL1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting FPRL1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery RPLEX HUM p38 pT180/pY182 ASY
The R-Plex Human p38 pT180/pY182 Assay from Meso Scale Diagnostics is a multiplex immunoassay kit for measuring phosphorylated p38 MAP kinase at Thr180 and Tyr182 in human cell lysates It uses electrochemiluminescent detection for rapid sensitive and reproducible analysis of p38 phosphorylation The kit includes a 96-well plate with capture antibodies detection antibodies and calibrator solutions It monitors p38 activation due to cellular stresses and inflammatory signals with a 2-hour sample incubation for high-throughput profiling
Abcam PKC Kinase Activity Assay Kit
PKC Kinase Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement